Theory of Chronic Sorrow as a Framework for Planning Care and Identifying Resources for a Family with a Child Diagnosed with Cerebral Palsy

Question
Theory of Chronic Sorrow as a Framework for Planning Care and Identifying Resources for a Family with a Child Diagnosed with Cerebral Palsy

Answer
Theory of Chronic Sorrow as a Framework for Planning Care and Identifying Resources for a Family with a Child Diagnosed with Cerebral Palsy
1. Introduction
It is important to identify the situational and emotional factors that contributed to the sorrow as it greatly affected where they moved into the next phase and how long they stayed in it. In this instance, the person may have just experienced an acute episode of multifactorial sorrow but will be seeking a way to alleviate the feelings.
CSS trajectory states that the person affected will move in and out of the 4 phases: shocked disorganization, searching and acceptance, moving between them with changes in situational and emotional factors. During the shocked disorganization phase, a parent may enter this phase when the child is first diagnosed with CP or ataxia. They may feel stunned, confused, or disheartened. A mother who participated in a longitudinal study on parental mental health when a child is diagnosed with cerebral palsy reported her feelings on receiving the diagnosis, saying “I was terribly, terribly upset because I thought that means the end of the world, of everything.” A predictor of chronic sorrow is a disappointment in the condition of the child compared with what was expected, so a parent who has been given a poor prognosis may feel the sorrow regardless of whether it was a realistic diagnosis. In a study conducted with a representative of children with militantly and severely impaired children with CP and their families in Scotland, feelings about CP and the prognosis of the child were very negative. Going on to the death of the child, this may be an example of an event triggering an episode of sorrow. At this phase, families for whom the prognosis is poor may move in and out of the episode of sorrow and into the searching and acceptance phase.
Eakes et al describe sorrow as an appropriate response to loss; however, sadness is only one emotion experienced during the sorrow response. It is classified as chronic when it recurs intermittently and a predictable time or after an event. CSS occurs in a number of situations in which families of children with cerebral palsy or spinocerebellar ataxia may feel sorrow.
CSS is a middle range nursing theory concerned with the long term effects of chronic sorrow on an individual and family. It was developed by Georgene Gaskill Eakes, Mary Lermnann, and Melba Cicierega in reaction to the overwhelming feelings of sadness they were experiencing in their current nursing practice. CSS is described as episodic. During the acute phase, the individual or family may experience intense feelings of sadness or depression, feelings of guilt or anger at the loss experienced, and difficulty accepting the limitations of the child or family member.
This essay will apply the chronic sorrow theory (CSS) to the case of a family with a child with spinocerebellar ataxia and discuss its relevance in terms of planning care and identifying resources. Spinocerebellar ataxia in children presents very similarly to cerebral palsy in that it is a motor disorder.
Theory of Chronic Sorrow as a Framework for Planning Care and Identifying Resources for a Family with a Child Diagnosed with Cerebral Palsy
2. Understanding the Theory of Chronic Sorrow
2.1. Definition and Background
2.2. Key Concepts and Components
2.3. Application to Families with a Child Diagnosed with Cerebral Palsy
3. Planning Care using the Theory of Chronic Sorrow
3.1. Assessing the Family’s Needs and Resources
3.2. Identifying Supportive Services and Programs
3.3. Developing Individualized Care Plans
4. Identifying Resources using the Theory of Chronic Sorrow
4.1. Medical and Therapeutic Resources
4.2. Educational and Developmental Resources
4.3. Financial and Legal Resources
5. Collaboration and Communication
5.1. Building a Collaborative Care Team
5.2. Effective Communication Strategies
5.3. Advocacy and Empowerment
6. Addressing Emotional and Psychological Needs
6.1. Providing Emotional Support and Counseling
6.2. Coping Strategies and Resilience Building
6.3. Balancing Hope and Realism
7. Enhancing Quality of Life
7.1. Promoting Independence and Functional Abilities
7.2. Accessing Recreational and Social Opportunities
7.3. Ensuring Inclusion and Community Integration
8. Continuity of Care and Long-Term Planning
8.1. Transitioning to Adult Care Services
8.2. Future Planning and Guardianship
8.3. End-of-Life Care Considerations

Threats to the Environment and Concerns

Question
We have discovered that there are numerous threats to the environment such as overpopulation, global warming, disposal of wastes, and even eco-terrorism.   Do you believe that these concerns are real or are they overstated to satisfy industrial and political agendas?  Of these problems, what concerns you the most?
Answer
1. Introduction
We find ourselves increasingly aware of major concerns about issues in the environment; some so widely known that those not “environmentally aware” are aware of only by name. Depletion of the ozone layer, widespread deforestation, air and water pollution, and the extinction of countless species are all leading examples of issues that have far greater effects than most of us realize. It is important to realize that every action has a reaction, even if we do not see the effects firsthand. These problems are all contributed to human interference in the environment, directly or indirectly. With an expanding population comes the need for more land to support the greater numbers of people, and while providing living space may be a direct cause of habitat destruction, the greater indirect cause is the need for more food sources and economic growth. Economic well-being is important to people all over the world, and this has driven the need for resources and energy. Using cleaner, sustainable energy sources and preventing energy waste can reduce harmful effects on the environment. Unfortunately, the trend is that richer countries are able to move in this direction of sustainable energy, while those countries and communities who are poor often rely on cheaper, dirtier energy sources. These contribute to not only pollution, but damage to ecosystems and health problems for the inhabitants. All these issues are deeply interconnected and are all contributors to the overall issue of global change. This report aims to explain the progression and interconnections of these issues in a logical manner, and to come out with a clearer understanding of the bigger issue at hand. The purposes of my work are to explain and demonstrate through various examples and statistics the vast array of environmental issues that are of global concern today. By increasing awareness and understanding of these issues, we can hope to enable a world that will seek to prevent further damage to the environment, and through active participation each make an impact as an individual. This leads to the next purpose of this work, to show that all these issues are of equal importance when considering their effects on the environment. It is quite often the case that people are aware of only the most publicized issues such as pollution and climate change, and while being big issues in themselves, they are all rooted from a wide array of other issues discussed in this report. An awareness of the global effects and solutions of these issues is necessary on all levels from the individual to the political, so in knowing that the big issue is global change, individuals who are better informed can make better choices and influence others to do the same.
1.1. Background
In the 1960s, concern for the environment resulted in an explosion of environmental legislation and the establishment of such agencies as the U.S. Environmental Protection Agency (EPA) and the UK Environment Agency. These agencies were designed to protect the environment and also to regulate the exploitation of the environment—development, industry, and land use. In many ways, given its concern for environmental sustainability—the ability to have our increasing material needs met without jeopardizing the quality of life now and for future generations—environmental economics is part and parcel of ecological economics. This field, which emerged in the late 1980s, is a policy-driven effort to change the way the economy affects the environment in largely the same way environmental economics emerged from the concerns of the 1960s regarding environmental degradation. The primary difference between the two is that while ecological economists are inclined to regulate the economy for the sake of environmental protection, environmental economists are inclined to change environmental policy using market-based tools. Despite the economic and environmental concerns, there are many who criticize the SMS process due to its overemphasis on science and economics and its failure to adequately involve the public in defining what is meant by the “healthy ecosystem” that is to be restored or preserved. This charge is founded on a belief that a healthy ecosystem is one whose preservation allows for human activities and settlement patterns that have already encroached upon the ecosystem. Though the SMS process is still new and its efficacy still unproven, the current trend in environmental management—whether market-based or regulatory—is consistent with the field of environmental economics and its underlying doctrine that the environment is valuable for the sake of human welfare. This holds great promise for graduates of economics programs.
1.2. Purpose of the Work
It is asserted that in order for a student to devise solutions for the future, he or she intending to begin a career in these areas should first have an understanding of the problems and their scope. Therefore, a major area of this work is to address the paradox that we face in 1992: that we know the environment is threatened, but we still do not understand precisely why this is so. It is hoped that these students will find the work directly and thoroughly addressing their needs and, in doing so, develop increased awareness and concern for their own environment.
The primary objective of this work is to bring the subject of environmental threats to the attention of students and, in so doing, foster concern and eventually collective action on the part of such readers. The importance of this issue is, of course, enormous, and it is the intention of the writer that some of this concern is reflected in the work to be found here. As a biology teacher, I have become increasingly aware of the desperation of the environmental problems facing the coming generation of students. Unfortunately, the subject is complex and interdisciplinary on one hand, while on the other, there is a wealth of biased and often contradictory literature available. It is therefore difficult to know where to begin in presenting a clear picture of the threats in 1992, and thus it is with some relief that the work is completed. The target audience, however, are not biologists, but rather students of environmental science, geography, economics, and social/policy studies studying within the tertiary sector.
2. Environmental Threats
2.1. Overpopulation
2.1.1. Impact on Resources
2.1.2. Pressure on Ecosystems
2.2. Global Warming
2.2.1. Rising Temperatures
2.2.2. Melting Ice Caps
2.3. Waste Disposal
2.3.1. Pollution of Land and Water
2.3.2. Health Hazards
2.3.3. Recycling Efforts
2.4. Eco-terrorism
2.4.1. Definition and Examples
2.4.2. Impact on Environmental Security
3. Debate: Real Concerns or Political Agendas?
3.1. Arguments for Real Concerns
3.1.1. Scientific Evidence
3.1.2. Global Consensus
3.2. Arguments for Overstated Concerns
3.2.1. Economic Interests
3.2.2. Political Manipulation
4. Personal Concerns
4.1. Evaluation of Threats
4.2. Identifying the Most Pressing Concern
4.2.1. Impact on Future Generations
4.2.2. Immediate Environmental Consequences
5. Conclusion

Resource: Substance Abuse Counseling Toolkit

question
create a resource that meets a gap or need at the counseling group for substance abuse that would help you or your site function more effectively. address the following prompts:
Resource name.
Resource purpose.
What gap or need does this resource meet?
Theoretical orientation the resource is grounded in.
Answer
1. Introduction
The aim of this toolkit is to provide direction and clarity in order to stimulate effective counseling for substance abuse. It is designed for professional counselors who work with persons with substance abuse/dependence and has recommendations that are consistent with current developments in the field of counseling. The toolkit will also provide someone who is new to substance abuse counseling with an invaluable resource for supervised clinical experience. Executive Directors of agencies that employ substance abuse counselors and counselors seeking to upgrade their skills will also find this toolkit both beneficial and resourceful. In working through the contents of the toolkit, it is most likely that consumers will receive the best care and the most healthy outcomes from their counseling.
Substance abuse counseling is one of the major treatments to fight against substance dependence and addiction. Disorders of substance or addiction can be best described as an individual having an unhealthy relationship with a particular substance which gives a false incentive. As counselors, it is essential for us to understand that our roles are becoming increasingly demanding. The National Institute on Drug Abuse and Alcohol (NIDAA) has recently developed a teaching guide for physicians on preventing adolescent drug abuse. This is an indication that society is recognizing the need for increasing awareness on the detrimental effects of substance abuse. Thus, before proceeding into the detailed information on tackling substance abuse, it is essential to have a clear understanding of what substance abuse counseling encompasses, what the outcomes are when cases are treated effectively, and lastly, address the needs or current trends in society.
1.1. Purpose of the Toolkit
This feedback also suggested that a manual was the preferred format rather than an online resource. So, printed materials are provided as much as possible. The toolkit is primarily intended for use by substance abuse counselors working with individuals, as opposed to groups, who are addicted to alcohol and/or other drugs. It may also be useful for counselors working with clients who have a dual diagnosis. The tools have been implemented and evaluated in a range of treatment settings. However, it is important to note that the toolkit was born out of work with people who have low motivation and limited readiness for change and may not be as relevant for clients who are further along in their change process.
The purpose of the Substance Abuse Counseling Toolkit is to provide practical guidance that will assist substance abuse counselors in treatment planning to help them be more effective and thus improve treatment outcomes. The tools provided in the toolkit are intended to supplement treatment and in no way replace professional judgment. The toolkit has been designed based on feedback from substance abuse counselors who wanted practical tools that were easy to use and relevant to their practice, to improve client retention and motivation.
1.2. Theoretical Orientation
In cognitive-behavioral approaches to substance abuse, the locus of treatment is on the identification, assessment, and monitoring of individual situations and emotions that lead to substance abuse. Two specific aims are to decrease the frequency of situations that lead to substance abuse and to reduce the likelihood of progression from initial use to dependence. This is accomplished through the development of coping strategies and skills training which are applied to relevant situations during and between sessions. Skills training may be directed at the acquisition of competencies the client does not presently have. Cognitive-behavioral approaches are often time-limited, focused, and present-motivated, steering clear of the client’s past.
Cognitive-behavioral, rational-emotive, and reality therapy are the theoretical frameworks used for the counseling and treatment of substance abuse. These specific theories were chosen because research shows that they are the most effective in treating the client population. The theoretical frameworks identified here may not be suited for all clients. Each theory comes with its own strengths and limitations. It is not expected that every counselor will or should change their theoretical orientation to these theories to work effectively with a substance abusing client. The hope is to provide the counselor with new tools and insights, to facilitate growth and change for the client.
Section 1.2: Theoretical Orientation
2. Assessment Tools
2.1. Substance Abuse Screening Questionnaires
2.2. Psychosocial Assessment Forms
2.3. Co-occurring Disorders Screening Tools
3. Treatment Planning
3.1. Goal Setting Worksheets
3.2. Treatment Plan Templates
3.3. Relapse Prevention Strategies
3.4. Crisis Management Plans
4. Psychoeducation Materials
4.1. Substance Abuse Education Handouts
4.2. Coping Skills Worksheets
4.3. Family Education Resources
5. Therapeutic Interventions
5.1. Cognitive-Behavioral Therapy Techniques
5.2. Motivational Interviewing Strategies
5.3. Mindfulness and Meditation Exercises
6. Group Therapy Resources
6.1. Group Session Plans
6.2. Icebreaker Activities
6.3. Discussion Topics for Substance Abuse Groups
7. Recovery Support Materials
7.1. Self-Help Books and Resources
7.2. Community Support Group Listings
7.3. Sober Living Resources
8. Documentation Forms
8.1. Progress Note Templates
8.2. Treatment Plan Review Forms
8.3. Discharge Summary Templates
9. Cultural Competence Resources
9.1. Cultural Assessment Tools
9.2. Multicultural Counseling Strategies
9.3. Diversity and Inclusion Training Materials
10. Ethical Considerations
10.1. Confidentiality Guidelines
10.2. Informed Consent Forms
10.3. Professional Boundaries Resources

Treatment Recommendations for Moderate Depression: Psychological and Biological Perspectives

question
Discuss treatment recommendations that are supported by the literature for a client facing moderate depression. Be sure to include suggestions from both psychological and biological perspectives. For which would you advocate most strongly, and why?
Answer
1. Psychological Treatment Recommendations
Recent meta-analyses and reviews have found that the effects of CBT for depression are large and that it is a highly effective treatment, particularly for outpatients. Beck’s original cognitive therapy (CT) model has been modified over the years, and there are now several manual-based therapies which are informed by CBT principles.
CBT also involves behavioral strategies, regular activity, and routine scheduling. It assesses the patient’s current level of activity and routine compared to what it was prior to the onset of depression or to a previously non-depressed person of the same age. It is suggested that a lack of positive activities or the adoption of avoidant behaviors may serve to maintain or further lower an individual’s mood. In these instances, activity scheduling will be used to plan and implement activities which are aimed to increase positive mood, a sense of achievement, or pleasure.
The most well-known cognitive-behavioral intervention for depression is the ABC model. This suggests that an individual’s thoughts (B) about an event or problem directly cause their emotional and behavioral responses (C). This is a result of the activating event (A). Often in depression, negative thoughts about self, the world, and the future are triggered by a negative event or situation. The ABC model is useful in discovering the relationship between thoughts and mood, which in turn can be used to test the validity of the particular thoughts. If the thoughts are found to be unrealistic or unhelpful, it is likely that there is a significant improvement in mood by changing them to a more realistic or helpful alternative. This method is usually used in conjunction with monitoring an individual’s mood and thought diary.
Cognitive Behavioral Therapy (CBT) is the most well-established evidence-based psychological treatment for depression in children, adolescents, adults, and older adults. It is designed to be a short-term, problem-specific approach which typically takes 12-16 weeks to complete. CBT is a highly directive therapy, which is based on the cognitive model: that depression is caused by a particular pattern of negative thinking which, in turn, leads to changes in behavior and mood. Treatment is focused on the present and is goal-oriented.
1.1. Cognitive Behavioral Therapy (CBT)
Cognitive Behavioral Therapy (CBT) is a widely used method for moderating depression (Gloaguen et al., 1998; Veale, 2008). Its effect has been demonstrated in numerous controlled trials and a variety of patient groups (Dobson, 1989; Hollon et al., 2002). CBT focuses on helping the patient to overcome a range of psychological difficulties. The concept of the therapy is that how we feel and what we do is determined by the way we think. This can be seen in Figure 1 when the patient has automatic negative thoughts about a specific situation. This will lead to a negative mood and no longer enjoying the activities that are usually found pleasurable. This can then spark a vicious cycle, making the patient become more and more depressed. The role of the therapist is to identify the negative thoughts and bring them to the attention of the patient. This can be achieved by collaboration with the patient using guided discovery. The automatic thoughts can be identified during the session or the therapist can assign the patient homework to monitor their moods at set times during the week and record the thought that coincided with the mood when it was lowered (Beck, 1995). Once the thought has been identified, the next step is to assess whether the thought is rational and if there is an alternative explanation. This is done by examining the evidence that the thought exists and creating a ‘thought record’. This thought record compares the positive and negative evidence for the thought and then looks for alternative explanations and if they are believed to be true. If the negative thought is deemed to be true, the third step is to try and decatastrophize and reduce the belief in the thoughts. This method of analysis also applies to the core beliefs of the patient and the way they view themselves in the world. The goal of this is to relieve the distress by resolving the psychological difficulties and disturbing thoughts which in turn will change the patient’s feelings and behavior (Beck, 1976). This can be contrasted to other therapies that focus on the past of the patient with the aim of bringing an understanding as to why the patient may be depressed. CBT only looks at the past in terms of identifying the cause of a psychological difficulty and does not dwell on historical issues. Beck’s model has been known to exhaust cognitive therapy and to try and define specific similarities that exist among patients with the same psychological difficulties, e.g. depression (Dobson, 1989). This has led to recent attempts of a more precise treatment based on an individual formulation. Step prologue CBT has also been proven to be an effective relapse prevention tool for recurrent depression and in many cases has a higher rate of improvement than various antidepressants (Bockting et al., 2009).
1.2. Interpersonal Therapy (IPT)
This IPT theory was developed in 1984 by Klerman and his colleagues in a medication treatment study at the University of North Carolina at Chapel Hill. Klerman’s group and an NIMH convened team subsequently refined, further developed and tested the psychotherapy over the next decade. IPT is a manual-based treatment with efficacy in the treatment of a range of psychiatric illnesses. It was first tested in major depressive disorder and then adapted for use in a variety of other mood and non-mood disorders. IPT has been most extensively tested in major depressive disorder where it is a monotherapy of equal potency to medication treatment and there is a wealth of converging evidence supporting its use. IPT theorizes that psychiatric illness can be termed a medical state with psychological symptoms. It posits that there are sometimes events which precipitate the onset of a psychiatric disorder, whether it be major events or a more insidious slow change. Once an episode is established, this will have effects on the interpersonal life situation of the sufferer. A depressive episode can have a profound effect on a person’s identity and character, and they may become this aggregated illness self. IPT understands the illness as separate from the patient and works via the management of specific symptoms and the prevention of future episodes to relieve the illness’s effect on the person’s identity. This effect is achieved through an effect on one of the patient’s four Interpersonal Problem Areas.
1.3. Mindfulness-Based Cognitive Therapy (MBCT)
Cognitive therapy provides a cognitive framework, which is treated as a simulation of the problems or a hypothesis (Beck, Rush, Shaw & Emery, 1979). This model is used to test the validity of the assumptions to identify areas of conflict in the brain and revise the assumptions (Teasdale, 1988). Although effective, it is difficult for the depressed patient to understand how this process can affect change, cognitive insight into one’s problems does not suffice to produce recovery from mood disorders. Instead, patients need to learn to disengage from the unconstructive modes of processing the facilitative of depressive relapse and learn a mode of processing that is more adaptive when recognizing early signs of progression into mood disturbance (Teasdale, Segal & Williams, 1995). Mindfulness is a mode of processing that is the opposite of autopilot, it enables cognitive reappraisal concerning the habit of a certain automatic process (i.e. becoming lost in rumination) and is seen as an alternative or precursor to CBT regarding cognitive change strategies (Teasdale, 1999). It is this principle that is the focus of Mindfulness-Based Cognitive Therapy (MBCT) for the prevention of major depressive relapse. MBCT was developed by Segal, Williams, and Teasdale (2002) as a psychological intervention designed to prevent the relapse of depression by teaching people with a history of depression to recognize the early signs of warning that a depressive relapse may occur and to disengage from the mode of mind that can draw them back into depression. This is achieved by cultivating mindfulness, an awareness that is in the present moment and adopting an accepting orientation to what is (Kabat-Zinn, 1990). The rationale of MBCT is in its understanding that a current episode of depression is characterized by automatic disengagement from the present moment into a rumination concerning the self and automatic assimilation of mood with its solutions being to attempt to fix the mood state by thinking and acting reactively to it, therefore avoidance of recurrence is best achieved by teaching patients to foster a mode of being that is detached, focused, and non-judgmental.
1.4. Behavioral Activation Therapy
Behavioral activation (BA), a component within the third wave of behavior therapy, constitutes a simple, yet elegant approach to treating depression. Its basis on the reinforcement contingency model and its use of functional assessment has allowed for vast developments within the treatment of depression and more importantly in the experimental and applied psychological field. From its theoretical roots to its current standing, BA has far-reaching implications in our understanding and treatment of depression. Simple, yet elegant, the reinforcement contingency model for depression states that depression is a disorder of low response-contingent positive reinforcement. In more understandable language, depression is a disorder occurring when positive outcomes in life no longer reinforce positive behaviors necessary for healthy living. With less activity and fewer chances for positive reinforcement from the environment, a person becomes subtly withdrawn or inactive. This state is self-perpetuating – continued inactivity leads to fewer experiences of reward or pleasure, resulting in depression that becomes more severe. The final result is always an increase in avoidance behaviors and generally low response-contingent positive reinforcement. This simple theory proposed by Lewinsohn represents a powerful explanation of the nature of depressive disorders and suggests an easy place to begin for treatment. Lewinsohn states that “a person who is depressed can be helped to recover if the positive reinforcement contingencies can be increased in the person’s life”. By targeting the issue of positive reinforcement, the hallmark of BA is its idiographic methodology which continues to influence assessment and experimental research.
2. Biological Treatment Recommendations
2.1. Selective Serotonin Reuptake Inhibitors (SSRIs)
2.2. Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs)
2.3. Tricyclic Antidepressants (TCAs)
2.4. Monoamine Oxidase Inhibitors (MAOIs)
3. Combined Psychological and Biological Treatment Approaches
3.1. Cognitive Behavioral Therapy with Medication
3.2. Interpersonal Therapy with Medication
3.3. Mindfulness-Based Cognitive Therapy with Medication
3.4. Behavioral Activation Therapy with Medication
4. Factors to Consider in Treatment Selection
4.1. Severity of Symptoms
4.2. Treatment History
4.3. Potential Side Effects
4.4. Patient Preferences and Values
5. Advocacy for Psychological Treatment
5.1. Efficacy of Psychological Approaches in Research
5.2. Focus on Long-Term Coping Skills
5.3. Potential for Personal Growth and Insight
6. Advocacy for Biological Treatment
6.1. Effectiveness of Medication in Symptom Reduction
6.2. Quick Onset of Action
6.3. Potential for Relief from Physical Symptoms

Sensitivity Analysis and Risk Incorporation in Capital Budgeting

Questions
Prepare a PowerPoint presentation on this topic. Include the following:
Title slide . 
5-7 content slides (Not including Title and Reference Slide) explaining the qualitative and quantitative steps necessary in conducting a Sensitivity Analysis. How can a project’s risk be incorporated into a Capital Budgeting analysis? Use concise bullet points on the slide and the Speaker Notes section to add details for each slide (this becomes your video “speech”).
 Minimum of 2 References.
A+ work required 
Must be plagiarism free. 

Answer
1. Introduction
In either case the evaluation is easier said than done. High risk investment opportunities are often rejected because it is difficult to quantify the risk and many different probability of success weighted cash flows could yield an unsatisfactory expected return. This is where risk incorporation in capital budgeting can provide a simple yet powerful tool to quantify risk and improve investment decisions.
It is impossible however, to predict the cash flows from investment project with perfect accuracy. Some factors are relatively certain to be correct in their expectation such as a firm’s term structure on their outstanding debt, the sensitivity of these cash flows given a particular interest rate could be measured quite precisely. A sensitivity analysis in this situation would involve a simulation to estimate the change interest rates given a time. On the other hand, if a firm is investing to launch a new product or service and have very little information about the market demand, the cash flows and expected rate of return from the opportunity are highly uncertain.
In recent years, sophisticated techniques for evaluating investment opportunities have been developed in the areas of sensitivity analysis and risk incorporation. Capital budgeting is by now a well-developed and critical organizational planning process field that helps to evaluate and select investment projects that will yield long run profits and/or cash flows that surpass a company’s cost of capital. At the heart of it, capital budgeting is a search for the rate of return, r, that will maximize the market value of a firm’s common stock. This involves analytical processes ranging from finding cost of debt or equity, to adjusting for risk in the cash flows that are being estimated from a particular investment opportunity. With the growth of computing power and information technology it has become more feasible intuitively and statistically evaluate a particular investment opportunity, incorporating modern portfolio theory and an overall trend toward higher risk investments. It is clear the importance of evaluating an investment’s risk and or return.
1.1 Purpose of the Presentation
Capital budgeting decisions are among the firm’s most critical strategic decisions because of their long term, high cost, and difficult-to-reverse nature. These characteristics make capital budgeting decisions the most likely to be erroneous of all decisions, thereby creating a significant business risk. It is for these reasons that the purpose of this presentation is to stress the importance of utilizing sensitivity analysis and risk incorporation when making capital budgeting decisions. This paper will first define and outline the importance of sensitivity analysis and risk incorporation when making capital budgeting decisions. Simulation analysis is an extension of these methods and is more complex and computationally demanding. Simulation analysis has been proven to be useful in the evaluation of projects and also is an effective method to incorporate risk. Simulation uses a model that describes the probability distributions of various input variables and generates a probability distribution for the NPV of the project. By creating a probability distribution of expected NPV, management can see the distribution risk of a project. Simulation can be very beneficial in risk assessment. Through these various methods, there are many ways to incorporate risk in the evaluation of a capital budgeting decision. The paper will also examine several different aspects of risk and how it can be incorporated into a project to increase the accuracy of the net present value. By doing this, we hope to inform financial managers of the benefits of using these methods and convince them to utilize them when making capital budgeting decisions. Following the examination of these methods, the paper will present an example that employs each method in a comprehensive manner so that the reader may better understand how to apply them. Finally, the paper will conclude with a summary of the methods and findings.
1.2 Importance of Sensitivity Analysis and Risk Incorporation
Sensitivity analysis is the effect of change in a dependent variable when an independent variable is changed. Such analysis is of crucial importance in taking investment decisions, especially in capital budgeting, because of the long-term and irreversible nature of the decisions. There is no point in taking a decision now that something cannot be done in the future, unless one can foresee that future conditions will make the thing more valuable to do then. Then postponing the decision is an immediate choice. If managers knew precisely the future economic conditions in terms of the variables such as costs of material, inflation rate, labor, etc., they could plug these into their capital budgeting model and then make an exact decision. Unfortunately, nobody knows the future and assumptions concerning the future are based on forecasting of the economic variables which are always subject to error. Now comes the question of what to do given an error in the forecast. Generally, the future variable is assumed to be more or less known and a range of values is assigned to it. Here, in between the decision made now and the variable, there exists an optimal strategy to reach the decision and the variable can be used as an independent variable. Given that capital budgeting decisions are usually taken over a period of time with the outlay of money at various times, the decision variable may be an outlay which can be seen as an investment at the different times and the variable its rate of return. Now a rate of return can be a very deciding factor to continue or abandon a certain investment and probability in the case of abandonment is that the investment is not worthwhile. To relate this to an earlier example, if an optimal strategy for a series of decisions exists and the probable rate of return on the investment is known, then a decision can be mapped to the rate of return and investment, and it is possible to simulate a series of decisions using the decision variables and stopping the simulation at a time if the investment is abandoned. Simulation techniques are very flexible and complicated ones can be used to directly replicate the real system and answer what would happen if a change were made.
2. Qualitative Steps in Conducting a Sensitivity Analysis
2.1 Identifying Key Variables
2.2 Determining the Range of Values
2.3 Assessing the Impact on Outcomes
3. Quantitative Steps in Conducting a Sensitivity Analysis
3.1 Assigning Probability Distributions to Variables
3.2 Performing Monte Carlo Simulations
3.3 Analyzing the Results
4. Incorporating Project Risk into Capital Budgeting
4.1 Evaluating Risk Factors
4.2 Adjusting Cash Flows and Discount Rates
4.3 Assessing the Impact on Project Viability
5. References

Should an incompetent inmate be forcibly medicated to restore competency for execution? Why or why not?

question 
Should an incompetent inmate be forcibly medicated to restore competency for execution? Why or why not?

Answer
Should an incompetent inmate be forcibly medicated to restore competency for execution? Why or why not?
1. Introduction
In the United States, criminal defendants may not be tried or punished for a crime while they are incompetent to do so. Godinez v. Moran, 509 U.S. 389, 391 (1993). This principle is well established and has been the law in the United States since the nation was founded. Incompetent criminal defendants may be confined to a mental health facility for treatment designed to restore their competency. During the past ten years, there has been a significant increase in the number of incompetent defendants whose cases are pending in the criminal justice system due to the shift in many states from custodial care in state hospitals to community-based treatment. It is estimated that there are presently over 15,000 defendants incarcerated in jails who are deemed incompetent to stand trial and are awaiting transfer to state mental health facilities (Slobogin, 1993). The increase in the number of incompetent defendants in the criminal justice system and the trend toward community-based restoration treatment has brought the issue before the courts and created a need for clear legal standards to govern the involuntary administration of antipsychotic medication to restore competency.
1.1 Definition of incompetence
Diminished Capacity Was formerly considered as a full defense. It is not incompetence in the sense that the defendant did not understand the charges or the legal process, but rather it is a non-capital murder charge with the premise that the defendant’s capacity was so diminished that he was unable to entertain the legal and moral intent requisite to the commission of the crime. Now regarded as a partial defense, this will still have bearing on execution-related issues as the defendant may have a later tenuous understanding of the reason for the sentence and still be more likely to plead incompetence to avoid execution. This would entitle him to a competency evaluation at the time of the proceeding.
Incompetency Incompetency is a legal rather than a psychiatric term. It refers to a defendant’s current state of mind rather than his factual knowledge in regard to the legal process and its implications. The criteria for deciding whether a defendant is competent varies from state to state, but the standard is generally a determination of the defendant’s rational and factual understanding of the proceeding and an ability to consult with his attorney. While the term is not ambiguous in itself, its interpretation and requisite level of functioning have yet to be universally agreed upon (Pinals & Mossman, 1986). When the Supreme Court first addressed the issue of competency in Dusky v United States (1960), they stated that a defendant is competent to stand trial if he has sufficient present ability to consult with his lawyer with a reasonable degree of rational understanding. Now, with the surge in research regarding competency restoration, more specific psycho-legal standards are being developed which better define various components of incompetence.
1.2 Importance of competency for execution
Proponents of restoration cite the therapeutic benefit of restoration efforts, the underlying goal of the criminal justice system to serve justice by punishing those responsible for wrongdoing, and general moral and ethical considerations relevant to equal and fair treatment of mentally disordered capital defendants. In contrast, critics of restoration believe that it is unfair and discriminatory to prolong the incarceration of mentally disordered persons solely because they are facing a capital charge. They argue that a mentally disordered defendant who is not facing a capital charge would not receive the same level of treatment simply to render him or her fit to stand trial, and that it is discriminatory to force treatment solely because execution is at stake (Grisso et al., 2005). This is complicated by the absence of a clear answer in the question of how long it is ethically and morally justifiable to try to restore competency for a consequence that becomes increasingly elusive and in effect serves as life without parole.
A finding of incompetence to be executed in the United States now results in indefinite detention (Sell v. United States, 2003). Because execution is the legally prescribed consequence for a capital crime, there is a public assumption that capital defendants are fit to be executed. Even though there is no medical evidence to suggest that persons with mental illness are at increased risk of danger to self or others compared with mentally competent persons (Appelbaum, 2001), there remains a societal appetite for removal of mentally disordered individuals from the community. People found incompetent to be executed are now often detained in high-security hospital facilities that resemble prisons more than therapeutic settings. In such locales they may be confined alongside persons committed through the criminal justice system, possibly resulting in long periods of incarceration with no hope of release (Slobogin, 1999; Bonnie et al., 2002). This is a far cry from the outcome in Jackson’s era, when a finding of incompetence led to quick release back to the community for those thought unlikely to regain their fitness (Perlin and Dorfman, 2009).
1.3 Ethical considerations
This leads us to ask the question of what is to be achieved by forcibly medicating an inmate. If it is said that it is done so the state can be “freed of the administrative burdens that court proceedings place on the state” and it “clears the docket of criminal cases,” then it would be argued that it is not in the interest of the inmate, but the state. This is shown by the fact that it creates an opportunity for the trial to continue should the inmate be restored to competency and lead to the charges not being dismissed. The death penalty is said to be a punishment for the seriousness of the crime committed and will be carried out in furtherance of justice.
Another important aspect to consider is whether forcibly medication violates the inmate’s Eighth Amendment rights. This is the right not to be subjected to cruel and unusual punishment. According to the Eighth Amendment, it would be unconstitutional to execute a person who is insane. Since medication is used in an effort to have the inmate carry on with the execution, it would be likely that the real intention would be to try and execute the inmate who otherwise would not be fit to do so. This is certainly unnerving and the use of the death penalty on an incompetent person may be considered cruel (2004). Say it is determined that a mentally ill inmate who was on death row would be treated and restored to competency. The trial court will lose jurisdiction of the inmate and he will be returned to the penal system because charges were not dismissed (1994). There is a real chance that the inmate who is only restored to competency to stand trial will have to face the front of court again and his charge and penalty will not be dismissed. This is another real possibility that medication will result in an incompetent person being sentenced to death.
2. Arguments in favor of forcibly medicating incompetent inmates
2.1 Ensuring justice is served
2.2 Upholding the rule of law
2.3 Providing closure to victims’ families
3. Arguments against forcibly medicating incompetent inmates
3.1 Violation of human rights
3.2 Ethical implications of involuntary medication
3.3 Potential for misdiagnosis or errors
4. Alternatives to forcible medication
4.1 Rehabilitation and treatment programs
4.2 Postponing the execution until competency is restored
4.3 Reviewing the validity of the death penalty
5. Legal considerations
5.1 Constitutional rights of inmates
5.2 Precedents and court rulings
5.3 Balancing the rights of the inmate and the state
6. Psychological evaluations and assessments
6.1 Diagnostic criteria for incompetence
6.2 Role of mental health professionals
6.3 Assessing the potential for restoration of competency
7. Implications for the criminal justice system
7.1 Impact on public perception and trust
7.2 Challenges in implementing forcible medication
7.3 Ensuring transparency and accountability
8. International perspectives on forcible medication
8.1 Comparison of policies in different countries
8.2 Human rights implications on a global scale
8.3 International standards and recommendations
9. Case studies and examples
9.1 Notable cases involving forcible medication
9.2 Outcomes and controversies surrounding these cases
9.3 Lessons learned and potential improvements
10. Conclusion
10.1 Summary of arguments for and against forcible medication
10.2 Considerations for future policy and legal reforms
10.3 Final thoughts on the ethical dilemmas involved

Technological Innovation in Care Coordination for Chronic Conditions

question
Technological Innovation in Care Coordination:
Research and discuss at least 3 emerging technologies that can be used to improve care coordination for chronic conditions.
Answer
1. Introduction
Technological innovation provides the potential for transforming health care delivery. Efficiency, improved access, support for patient self-care, and better clinical outcomes are the promise of informatics-enabled care. Most literature on this topic focuses on the actual technologies. For example, a recent special issue of the Journal of the American Medical Informatics Association was devoted to the topic of home monitoring, with a number of these articles discussing the technical aspects of various informatics solutions. Other work has focused on the development of tools for shared decision making, again concentrating on the specifics of the technologies involved. There is a more limited amount of work looking at the process of technological innovation. In his blended care model, Erlingson states that new technologies must be tested and integrated into patient care in a systematic way, something he has developed but not yet fully written up that is something we hope to discuss with him. Lorenzi and Riley have done significant work in the area of Action Research, developing and testing various methodologies to promote success in implementing new informatics tools. This work involved an 18-month investigation on the implementation of work changes and computer-based patient records at Vanderbilt University, which resulted in an increased understanding of the process of change as it related to information systems. This work was a series of studies to learn better ways of making systematic changes to better the way care is delivered using information technology. While it focused on the process of change, it did not focus on an innovation in care coordination, nor was it really a study designed to innovate a technology.
1.1 Background
Effective care coordination has been pinpointed as a means to improving care for those with chronic conditions. Care coordination is defined in a number of ways by healthcare professionals and researchers. A simple definition is that care coordination organizes patient care activities and information to facilitate the appropriate delivery of healthcare services. A somewhat more complex definition by McDonald et al. states that care coordination is the deliberate organization of patient care activities between two or more participants involved in a patient’s care to facilitate the appropriate delivery of healthcare services. Organizing care involves the marshalling of personnel and other resources needed to carry out all required patient care activities and is often managed by the exchange of information among participants involved in a patient’s care. Care coordination has been said to identify the patient’s needs and arrange and monitor the services of a care plan in a coherent and cost-effective manner.[4]
Improvements in life expectancies over the past decade have led to an increase in the number of individuals living with debilitating chronic medical conditions. A chronic condition is defined as a medical illness or impairment that lasts six months or longer, is not self-limiting, and often necessitates ongoing medical management. It is estimated that over 90 million individuals live with chronic illnesses in the United States, with that number expected to increase.[1] In the state of Washington alone, the population of individuals over age 65 is expected to increase by 68% between 2000 and 2020, resulting in a sizable increase in the number of individuals living with chronic medical conditions who, at ages 65 and older, account for approximately 75% of all healthcare expenditures.[2] Chronic conditions are a major public health issue and the primary reason for rises in healthcare costs. It therefore comes as no surprise that the Institute of Medicine has recently called for a redesign of the healthcare system, saying that the current care for individuals with chronic conditions is often inadequate and that innovation is urgently required.[3]
1.2 Purpose of the Study
Large segments of the population in the United States are affected by chronic conditions, and the numbers are expected to rise in the coming years. It is estimated that 125 million Americans are currently living with some type of chronic condition. This number is expected to grow by more than 25%, to 157 million, by 2020. It is also estimated that 1 in 4 people have two or more chronic conditions. The care of individuals with chronic conditions poses a significant challenge to the US healthcare system. Coordinating care for individuals with chronic conditions is particularly difficult for a number of reasons. Firstly, chronic conditions tend to be waxing and waning, which makes predicting and planning for healthcare needs more difficult. Secondly, chronic conditions often necessitate care from multiple healthcare providers across a number of different healthcare settings. Finally, individuals with chronic conditions are more likely than healthier individuals to suffer from functional limitations. The combination of these three factors makes the care of individuals with chronic conditions costly and fragmented. Research has shown that well-coordinated care can improve care quality for those with chronic conditions, although what constitutes effective care coordination has been insufficiently investigated. Advances in information technology have the potential to greatly improve care coordination. Given the assessed need for improvement in care coordination for chronically ill individuals, it is both surprising and encouraging that care coordination is one of the six aims for improvement in the new Affordable Care Act. The purpose of this study is to explore how information technology can be utilized to improve care coordination for individuals with chronic conditions. This will be examined through a mixed methods analysis of a care coordination intervention at Group Health Cooperative. The specific objectives of this study are as follows: – To examine the use of IT in care coordination for patients with chronic conditions. – To evaluate the impact of an IT-based care coordination intervention on patient and provider outcomes. – To understand the process by which an IT-based intervention can affect change in care coordination.
2. Emerging Technologies for Care Coordination
2.1 Telemedicine
2.1.1 Remote Patient Monitoring
2.1.2 Video Conferencing
2.2 Artificial Intelligence
2.2.1 Predictive Analytics
2.2.2 Natural Language Processing
2.3 Wearable Devices
2.3.1 Smartwatches
2.3.2 Fitness Trackers
3. Benefits of Using Emerging Technologies
3.1 Improved Communication and Collaboration
3.2 Enhanced Patient Engagement
3.3 Timely and Accurate Data Collection
3.4 Personalized Care Plans
4. Challenges in Implementing Emerging Technologies
4.1 Privacy and Security Concerns
4.2 Cost and Resource Allocation
4.3 Training and Adoption
5. Case Studies
5.1 Case Study 1: Successful Implementation of Telemedicine
5.2 Case Study 2: AI-Driven Care Coordination in a Hospital Setting
5.3 Case Study 3: Wearable Devices for Remote Monitoring
6. Future Directions and Potential Impacts
6.1 Integration of Emerging Technologies with Existing Healthcare Systems
6.2 Policy and Regulatory Considerations
6.3 Long-term Effects on Care Coordination and Patient Outcomes
7. Conclusion

Technology and Informatics in Evidence-Based Practice

Question
For this discussion, consider the ways in which technology and informatics are used to support evidence-based practice. Please address each of the following questions in your discussion response for this week:
Choose a specific evidence-based practice (examples: CAUTI reduction, sepsis protocol, SCIP protocol, bedside shift report, etc.).
Describe how technology and informatics are used to support the interventions used in practice?
Describe how employing evidence-based practice guidelines improve patient outcomes?
What benefits and challenges have you experienced with (the integration of) information technology in your practice?
What strategies did you, or could you, use to overcome these challenges?
Answer
1. Introduction
Informatics is any practice that involves the use of information. It involves using information and applying cognitive and practical skills for manipulating the information (knowing), and comparing this with the various health sciences aiming at a better understanding of health problems and evidence leading to decisions or actions (doing). Informatics has a broad application across health care including management data on service utilization, assessing population health needs, disease management, and consumers making informed decisions about their health. For EBP, informatics can provide enhanced access to and dissemination of information. It provides means to the management of vast volumes of information and presenting this at the right time in the right place to enable high-quality decisions. Today with the internet, the amount of information is huge, informatics can help break this down and provide the correct research for the right area in the instance of say a clinical encounter. For evidence-based clinical decisions, there are methods of decision analysis and modeling using probability to predict the best course of action and assess potential outcomes. Finally, informatics can provide monitoring and audit against best evidence through various means of information, to determine if practice is effective and to make improvements in areas of sub-optimal care. All of these methods are a vast improvement for integrating evidence into practice in contrast to the traditional methods of medical education which focus on retraining the facts to be recalled at a later time.
Evidence-based practice (EBP) involves making clinical decisions based on the best available evidence, using it alongside clinical expertise and patient values. Evidence-based practice is not new, but it is now receiving increasing attention in health care as medicine becomes more complex with more decisions and therapy options. There is some resistance to EBP which arises from the ‘art’ of medicine with its individualistic craft approach and its tradition of passing down information from mentor to protégé. We must stress, EBP is not about cookbook medicine. EBP is about integrating individual clinical expertise with the best available external clinical evidence from systematic research. In ideological terms, it aims to keep the ‘art’ of medicine while emphasizing some of the science-based aspects in the ‘art’. For medical practitioners, it is applying a conscientious, explicit, and judicious process in making decisions. This will help to improve the quality of their clinical judgments and keep up to date with the new and relevant research. Evidence-based practice is patient-centered. It’s about providing care that is of the best quality with the understanding of the potential risks and benefits for treatment and non-treatment for the patient, with the use of informed consent. For the patient, it means receiving high-quality care which is up to date with minimal error in diagnosis and treatment with the view that will increase the length and quality of life. With the explosion of research, medicine has a struggle to change practice. Major barriers include problems with the volume and lack of awareness of new research, and the lack of resources and time, so changing practice can be quite slow. Measures need to be taken and doctors must come to understand the research and change their practice, and patients must understand that the quality of care is directly linked to the care that’s been proved to be effective through research.
1.1 Importance of Evidence-Based Practice
The practice of evidence-based medicine can be regarded as a systematic and disciplined way of evaluating clinical problems and practice. EBM is a lean, mean patient care providing machine. It allows the clinician to quickly, efficiently, and effectively weigh the pros and cons of a particular treatment. If there are no current RCTs suggesting the use of a particular medication, the clinician is able to use clinical experience, hierarchy of evidence, and patient values to make a very informed decision. Evidence-based medicine involves conscientious, explicit, and judicious use of current best evidence in making decisions about the care of individual patients. The practice of EBM is very important, and in fact, it’s the backbone of our internal medicine residency program. Because many different treatments lead to similar outcomes, we want to ensure that we’re providing the most efficient and effective care for our patients. This residency program is going to teach us how we can acquire the best evidence, how to assess its validity and usefulness, and how to apply it when making medical decisions. The concept of EBM and steps involved are summarized in the article: “Evidence-Based Medicine: What It Is and What It Isn’t” (Sackett, 1996). The practice of EBM has proven successful in many surgical and medical specialties. It’s been shown to reduce costs, improve the quality of intervention, and lead to better patient outcomes. In a study conducted by David L. Berger, M.D., MS (2003) and colleagues, it was found that EBM is most successful when it involves the cooperation of clinical scientists, biostatisticians, and personnel in biomedical informatics. To be EBM practitioners, we must become efficient in avoiding outdated practice habits and to stay informed on recent developments and evidence across all areas of patient care. This is no easy task, but with practice and familiarity, it becomes second nature.
1.2 Role of Technology and Informatics
Technology has come a long way and has become more affordable and easier to use. In a recent survey of US adults, 72% of internet users said they looked online for health information within the past year. One of the many reasons why they are seeking health information online is that it has become easily available and convenient. The use of computers and mobile devices can now allow practitioners and patients to access health information from any location with internet wifi or cellular access. This is an important determinant as with EBP, it is not only important to access evidence, but it is also important to be able to apply and integrate it into clinical practice. This improved access to technology can dispel the restrictive view that evidence-based practice can be limited to only using research when it is available. In a clinical scenario, it is not uncommon to encounter situations where there is no clear evidence or evidence-based guideline to best manage a patient. Often without easy access to research materials, decisions are often defaulted to previous practice habits or even mere intuition. With improved access to information technology, such a situation can prompt the practitioner to search for evidence at the point of care, and thus, will close the gap between practice and research. As a matter of fact, it is suggested that the best method to promote evidence-based practice is to teach clinicians how to form questions about clinical practice and search for the answers. With the improved availability of research materials and evidence, technology can ultimately teach us how to think critically.
The concept of evidence-based practice (EBP) has created a substantial impact in the medical industry. Though its formulation has been a long and rough process, it has proven itself to be a critical player in improving the existing healthcare system, which is filled with outdated practices that are either flawed or have been rendered obsolete by newer and more effective interventions. According to the definition provided by Sackett and colleagues, EBP is “the conscientious, explicit and judicious use of current best evidence in making decisions about the care of the individual patient. It means integrating individual clinical expertise with the best available external clinical evidence from systematic research.” The expected outcome of EBP is to improve the quality of clinical practice and ultimately improve patient outcomes. It is clear that the goals of EBP correspond with the needs of the healthcare system, and it’s important to recognize that technology and informatics is a key driver behind the success of EBP and the execution of its objectives.
2. Specific Evidence-Based Practice
2.1 Selection of a Practice
2.2 Overview of the Chosen Practice
3. Technology and Informatics in Practice Interventions
3.1 Integration of Technology in Practice
3.2 Informatics Support for Practice Interventions
3.3 Benefits of Technology in Practice Interventions
4. Improving Patient Outcomes through Evidence-Based Practice
4.1 Understanding the Impact of Evidence-Based Practice
4.2 Patient Outcomes and Evidence-Based Guidelines
5. Benefits and Challenges of Information Technology in Practice
5.1 Benefits of Information Technology
5.2 Challenges Faced in Integrating Information Technology
6. Strategies to Overcome Challenges
6.1 Identifying and Addressing Barriers
6.2 Training and Education for Information Technology
6.3 Collaboration and Support
7. Conclusion

Infectious Diseases and Viruses

question

1- What does the term ‘germs’ usually refer to? 
2- What do all germs have in common? 
3- Define the term ‘modes of transmission’ and give an example. 
4- What is a major disadvantage to a virus, if it replicates too much, too quickly? 
5- If there’s too little of a virus, what is a disadvantage (to the virus) if you don’t experience any symptoms? 
6- List the characteristics of a successful virus. 
7- What does the trade-off hypothesis predict for rhinovirus? 
8- Why does the malaria virus do not require a mobile host? 
9- What can we do to minimize the harmfulness of infectious diseases?
Answer
1. Introduction to Germs
It is highly improbable that a person of adult age could have lived in a household in a semi-sterile environment or worked in an industry which has top-notch cleanliness. Even though people may not be able to visualize germs, mold, and other biohazardous agents, they are always aware of the precautionary methods and practices which aim to bound these unwanted visitors from the realm of clean indoor living or working space. Whether it is teaching children to wash their hands before meals or, in some cases, after, using antibacterial soaps and lotions or spraying down kitchen and bathroom surfaces with chemical disinfectants, people are fighting a seemingly never-ending battle to rid our living spaces of germs. With the recent outbreak of diseases such as SARS, H1N1 virus, and increasingly high numbers of food poisoning cases, it is becoming more important to have a comprehensive understanding of what a germ is and its role as a causative agent of disease. The infamous people of the pre-germ theory era conducted acts such as opening the abdominal cavities of the deceased using bare hands and with no more protection than a blood-stained apron, to cutting the utensils and items used in surgery and not washing them, have an extreme appreciation of what a germ is and the effect of its presence.
1.1. Definition of ‘Germs’
Enough to be seen with the unaided eye. We will call these invisible living beings germs. This definition includes bacteria, fungi, various parasites, and viruses. Germs are limited by being too small to see without a microscope. Bacteria are made up of only one cell, but they are all around us and on us and even in us. Fungi are multi-celled plant-like organisms (such as mushrooms) that also include single-celled species (such as yeasts) and are also found everywhere, often in the form of mold. Many parasites are large enough to be seen. For example, worms are parasites. But this definition includes some parasites that are too small to be seen, such as the ones that cause malaria, which are single-celled organisms called plasmodia. The only exception to this definition is viruses, which are smaller than the smallest cells. While not all viruses are germs in the usual sense, this definition includes them because they are the cause of very many infectious diseases, and they are the only living organisms whose natural state is to exist only inside cells. Viruses are difficult to classify as microorganisms, as they are not truly alive. But they are invariably disease-causing, and this is the key attribute to germs in the context of infectious diseases.
1.2. Common Types of Germs
Viruses are small capsules containing genetic material. They are parasites in other organisms, including people, causing a range of diseases. The common cold, influenza, and warts are all caused by viruses. A virus can only reproduce within the cells of the host it invades, as it reprograms the cell to produce the components necessary for its replication. In most cases, viruses damage or kill the cells, then lie dormant for a period of time before reappearing, causing extensive long-term damage. The cell damage and the immune system’s response to the infection cause the symptoms of viral diseases. The immune system usually eliminates the virus from the body, and the infection is resolved. However, in some cases, such as HIV and Epstein-Barr, the virus evades the immune system, and the infection becomes chronic. Antiviral drugs are selective for viruses in that they can impair virus replication without harming normal host cells. However, due to the difficulty in targeting the viruses and not the host cells, these drugs often have limited effectiveness.
Bacteria are tiny, one-celled creatures that get nutrients from their environments in order to live. In some cases, that environment is a human body. Some bacteria actually cause disease, while others are helpful and even necessary to good health. Lactobacillus bulgaricus, for example, lives in the intestines and helps digest food. The bacteria in yogurt is probably the most known example of Lactobacillus bulgaricus. A few bacteria, such as the mycobacteria, are not harmful in general but can cause disease in a person whose immune system is not working properly. For example, Mycobacterium avium-intracellulare can cause a serious disease. More information is available on this in the Immune System and Disorders Article. Bacteria can cause many types of infections varying in severity. Infections occur as the bacteria try to make the body an environment more suitable for them to live in, reproducing and furthering their harmful effects. In infecting the body, bacteria can damage cells or interfere with cell function. They may release toxins which can damage the whole body. This then becomes a generalized infection. Symptoms of infection can vary but often include inflammation, fever, and fatigue. Bacterial infections are usually treated with antibiotics, which are chemicals designed to destroy or weaken the bacteria. High-level or broad-spectrum antibiotics are effective against a wide range of bacteria, and low-level antibiotics are often used to keep certain bacteria at bay. Amoxicillin use for prevention of Urinary Tract infections is an example of this. Antibiotics seldom have no effect on symptoms since they may cause removal of the bacteria and toxins that have caused damage or particular symptoms. Antibiotics have had a major impact on the length and severity of bacterial infections and on general public health.
Many people are familiar with the term “germs” referring to the tiny, microscopic organisms that cause disease. Until the invention of the microscope, scientists did not realize that germs existed, and people thought that disease was caused by bad air, spirits, a punishment from a god or simply fate. However, we now know that 4 main types of germs cause infectious disease. These are bacteria, viruses, fungi, and protozoa. Each of these types has its own structure, behaviors, and effects on the human body.
1.3. Role of Germs in Infectious Diseases
The organisms explained in the previous sections cause disease because they circle the primary location of the infectious organism that multiplies and causes trouble for the host. Now, disease is essentially a battle between two invasive organisms: the germ and the human. Disease occurs when the germ is successful in the battle with the human. The severity of that battle is what determines the severity of the disease. They are successful at causing disease when there is a portal of entry available to them. They are able to attach to the cells, grow and multiply, remain undetected by the immune system, and then cause damage to the cells and tissues. Germs in general are very adaptable, and that is why they are very successful at causing disease. Unfortunately, not all new strategies for the germ are successful in overcoming the immune system and resulting in disease. An example of this is the common cold, where there are over 200 different viruses that cause cold-like symptoms. Usually, it is insufficient in overcoming the immune system to cause serious illness, and symptoms of disease are only mild. This is known as colonization of the host, and many common diseases are simply a result of the germ trying to colonize and the battle between the germ and human causing only mild disease.
2. Common Characteristics of Germs
2.1. Key Features of Germs
2.2. Similarities Among Different Types of Germs
2.3. Importance of Understanding Germs’ Commonalities
3. Modes of Transmission
3.1. Definition of ‘Modes of Transmission’
3.2. Examples of Different Modes of Transmission
3.3. Significance of Understanding Transmission Methods
4. Viral Replication and Disadvantages
4.1. Consequences of Excessive Virus Replication
4.2. Negative Impact of Rapid Virus Replication
4.3. Effects of Overabundance on Virus Survival
5. Implications of Low Virus Levels
5.1. Disadvantages of Insufficient Virus Presence
5.2. Lack of Symptoms and Virus Survival
5.3. Importance of Detecting Low Virus Levels
6. Characteristics of Successful Viruses
6.1. Traits of Highly Effective Viruses
6.2. Factors Contributing to Virus Success
6.3. Understanding Successful Virus Traits
7. Trade-Off Hypothesis for Rhinovirus
7.1. Predictions Based on the Trade-Off Hypothesis
7.2. Implications for Rhinovirus Survival
7.3. Analyzing the Trade-Off Hypothesis in Rhinovirus
8. Malaria Virus and Host Mobility
8.1. Factors Influencing Malaria Virus Transmission
8.2. Lack of Mobile Host Requirement in Malaria Virus
8.3. Understanding Malaria Virus Transmission Mechanisms
9. Minimizing Harmfulness of Infectious Diseases
9.1. Strategies for Controlling Infectious Diseases
9.2. Importance of Preventive Measures
9.3. Promoting Public Health Initiatives

Influence of Culture on Cross-Border M&A Activity

QUESTION
How does culture influence cross-border M&A activity? Illustrate this relationship using examples, either real (even anecdotal if you have any) or conceptual. How do similar and dissimilar cultures affect pre- and post-merger performance?
ANSWER
1. Introduction
Organizational culture will not be the main focus of the study since its impact on M&A activity has been studied in depth in management literature. A holistic case study of the merger between the German company Daimler-Benz and US firm Chrysler will be used since this is considered a classic example of clash of national cultures. The inductive methodology used in the Daimler-Chrysler case will be initially used in the attempt to separate national culture from organizational culture and study its direct impact on M&A activity. Any findings and conclusions drawn from this case study will be initially tested against any theory provided in management literature. The aim in the end is to possibly come up with a new model explaining the impact of culture on M&A activity, which will be a useful framework for managers in the future.
In this research paper, the focus will be on studying the importance of culture in M&A activity. The objective of the paper is to separate the impact of national culture from organizational culture on M&A activity. The distinction between the two is important since national culture is considered an unmanageable force a firm encounters when it operates in a foreign environment, while organizational culture is a manageable force the firm can manipulate in order to coordinate and integrate activities when working with a potential partner.
Globalization has led to ever-increasing business activity across national borders. This has fueled the pace of cross-border mergers and acquisitions (M&A) in today’s global economy. Culture has been identified as a critical factor which has a significant impact on the outcome of international business activity. Cross-border M&A is an activity that takes place when a company from one country merges or takes over the assets of a company in another country.
1.1 Importance of Culture in Cross-Border M&A
Despite the prevalence of literature regarding the role culture plays in business, in particular cross-border mergers and acquisitions (M&A), it remains a relatively unexplored and underestimated factor in comparison to other theoretical lenses such as synergy or agency theory. It is widely recognized that national cultural differences are to be found in the differing thoughts, actions, assumptions, and a range of behavioral and material artifacts (Hofstede, 2002); all of which are key components of a society. That said, the fragmented and multidisciplinary nature of cultural theory development to date, it has yet to be fully integrated into M&A research and practice. However, there are various instances within the literature that infer assumptions to the effects of culture on M&A. For example, it is often cited as a reason for failure (Cartwright and Cooper, 1992), a costly barrier to be overcome during post-merger integration (Haspeslagh and Jemison, 1991), or a factor that should be included in the pre-acquisition screening process (Prahalad and Doz, 1987). While these examples bestow importance, it is not sufficient evidence to unequivocally prove it as a critical factor in M&A, and to date there is no defined framework or model that seeks to understand culture with respect to an entire M&A process. This is not to say cultural impact is always negative; a recent study by Stahl and Voigt (2008) identified that high cultural differences between two companies could lead to a lesser likelihood of bidder overpayment in an acquisition deal. However, the context of this result was within financial terms rather than the long-term integration process, and as aforementioned, this is not a widely explored area. With this considered, on the basis that culture is a central aspect of national identity, it can be viewed as a key and relevant aspect to any process involving two differing nations or organizations. This does not necessarily imply that any M&A between two differing national organizations will be heavily influenced by culture, for culture is a very broad and subjective concept, and there are varying levels of cross-border M&A; hence, the theory suggests that cultural impact will vary depending on the circumstance.
1.2 Objectives of the Study
The primary goal of this project is trying to figure out the impact of national and organisational culture on cross-border mergers and acquisitions, in the hope that better understanding of the influence of culture can help in avoiding some of the obvious pitfalls, and lead to successful integration which is the ultimate mark of a successful M&A activity. As this is an exploratory study, no hypothesis is put forward as it seeks to find new insights and information in the hope of forming a new theory. This has led to much of the research being in a more qualitative manner, although many questions do lend themselves to quantitative analysis. Measures of national culture provide a good base to look at the cultural issues, and matched-pair studies of companies involved in M&A activity can give good indications of the influence of culture on M&A and what actually occurs during the process. By looking at the level and nature of the increased M&A activity in the last 15 years, from the standpoints of both acquiring company and target firms, insights can be gained as to why the increase in M&A activity has led to mixed results, and how culture may be a key factor regarding this. Being an exploratory study, no specific culture dimension or issue is singled out, rather it looks at broad overall influence that culture may have at the national and organisational levels. A literature review is done on the failures and success stories of M&A activity, and there have been many case studies that offer comparisons such as two companies of different nationalities, one which has succeeded in M&A activity and one which has not. This provides much insightful data for the matched-pair studies and goes towards meeting the goals of this research.
1.3 Methodology
Another belief is that the culture of a society can be described by the values and norms present (Tayeb, 2000). Although it is possible to measure culture directly with various means, indirect measurement is probably the most effective, possibly using a society’s political or legal systems as a function of the culture it represents. Due to the breadth of values, norms, and the multi-level nature of culture, measuring the exact effects of culture on M&A activity is problematic and has only been extensively attempted by the very biggest firms in simulated training exercises. This encompasses a number of variables that would be best done by multiple means and at various levels, to provide a comprehensive understanding of the various issues involved. This too is evident throughout the research, as nearly all the micro-level events that created problems during M&A could always be related back to a difference of values or norms.
The research’s underpinning philosophy is the belief that culture affects behavior. This belief was supported by Yalcintas (1981), Guy and Beddow (1983), and Seth (1986). Yalcintas suggested that M&As were of an international nature and therefore present many problems in terms of differences in national policies, mentalities, and ways of doing business. Guy and Beddow and Seth also suggested that the variables of nationality and culture were of major import in M&A activity and provide one of the better frameworks within which to understand M&A behavior (Guy and Beddow, 1983; Seth, 1986 cited in Cartwright and Cooper, 1993). This belief was held throughout the EFA and case study and remained evident in the various responses received during the research, and some of the contradictions and practical problems that were found; each of which was possible to explain by cross-cultural differences. If we consider Schneider and Barsoux’s argument that cultural variation causes different mental programming, which creates ambiguity in cross-cultural encounters (Schneider and Barsoux, 1997), i.e. different behavioral patterns and an expectancy of behavior between parties in the M&A, the importance of effects of national factors and culture in M&A become more transparent.
II. Essay Summary
2. Theoretical Framework
2.1 Definition of Culture
2.2 Cultural Dimensions
2.2.1 Power Distance
2.2.2 Individualism vs. Collectivism
2.2.3 Masculinity vs. Femininity
2.2.4 Uncertainty Avoidance
2.2.5 Long-Term Orientation
3. Cultural Influence on Pre-Merger Performance
3.1 Cultural Due Diligence
3.2 Cultural Compatibility Assessment
3.3 Communication and Integration Challenges
3.4 Leadership and Decision-Making Styles
3.5 Employee Motivation and Engagement
4. Cultural Influence on Post-Merger Performance
4.1 Organizational Culture Alignment
4.2 Change Management Strategies
4.3 Employee Retention and Talent Management
4.4 Knowledge Transfer and Learning
4.5 Performance Measurement and Control Systems
5. Case Studies
5.1 Cross-Border M&A Success Stories
5.2 Cross-Border M&A Failures
5.3 Lessons Learned
6. Conclusion
6.1 Summary of Findings
6.2 Implications for Cross-Border M&A Practitioners
6.3 Recommendations for Future Research