Design And Validation Of Cleanrooms For Interferon-Alpha Manufacturing

BackgroundInterferons are probably the first cytokines to be discovered. During the 1950s, scientists observed various animal cells when exposed to the virus, they automatically become resistant to attack by other viruses(Hanaoka and Takeuchi, 2013). This resistance was induced by interferons secreted by virally infected cells.  Interferons are produced by different cell types of which they exhibit their biological effects in various wa…